Spine Patterning Is Guided by Segmentation of the Notochord Sheath

Spine Patterning Is Guided by Segmentation of the Notochord Sheath

Summary: The spine is a segmented axial structure made of alternating vertebral bodies (centra) and intervertebral discs (IVDs) assembled around the notochord. Here, we show that, prior to centra formation, the outer epithelial cell layer of the zebrafish notochord, the sheath, segments into alterna...

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Bibliographic Details
Main Authors: Susan Wopat, Jennifer Bagwell, Kaelyn D. Sumigray, Amy L. Dickson, Leonie F.A. Huitema, Kenneth D. Poss, Stefan Schulte-Merker, Michel Bagnat
Format: Article
Language:English
Published: Elsevier 2018-02-01
Series:Cell Reports
Subjects:
notochord sheath
segmentation
spine
vertebrae
intervertebral disc
Notch
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718301487

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