TNFα transport induced by dynamic loading alters biomechanics of intact intervertebral discs.

TNFα transport induced by dynamic loading alters biomechanics of intact intervertebral discs.

Intervertebral disc (IVD) degeneration is an important contributor to the development of back pain, and a key factor relating pain and degeneration are the presence of pro-inflammatory cytokines and IVD motion. There is surprisingly limited understanding of how mechanics and inflammation interact in...

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Bibliographic Details
Main Authors: Benjamin A Walter, Morakot Likhitpanichkul, Svenja Illien-Junger, Peter J Roughley, Andrew C Hecht, James C Iatridis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4348425?pdf=render

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