Evolutionary and functional impact of common polymorphic inversions in the human genome
Inversions are a little-studied type of genomic variation that could contribute to phenotypic traits. Here the authors characterize 45 common polymorphic inversions in human populations and investigate their evolutionary and functional impact.
Main Authors: | Carla Giner-Delgado, Sergi Villatoro, Jon Lerga-Jaso, Magdalena Gayà-Vidal, Meritxell Oliva, David Castellano, Lorena Pantano, Bárbara D. Bitarello, David Izquierdo, Isaac Noguera, Iñigo Olalde, Alejandra Delprat, Antoine Blancher, Carles Lalueza-Fox, Tõnu Esko, Paul F. O’Reilly, Aida M. Andrés, Luca Ferretti, Marta Puig, Mario Cáceres |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2019-09-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-019-12173-x |
Similar Items
-
Functional Impact and Evolution of a Novel Human Polymorphic Inversion That Disrupts a Gene and Creates a Fusion Transcript.
by: Marta Puig, et al.
Published: (2015-10-01) -
Malaria was a weak selective force in ancient Europeans
by: Pere Gelabert, et al.
Published: (2017-05-01) -
Mitochondrial DNA from El Mirador cave (Atapuerca, Spain) reveals the heterogeneity of Chalcolithic populations.
by: Daniel Gómez-Sánchez, et al.
Published: (2014-01-01) -
ProSeeK: A web server for MLPA probe design
by: Villatoro Sergi, et al.
Published: (2008-11-01) -
Validation and genotyping of multiple human polymorphic inversions mediated by inverted repeats reveals a high degree of recurrence.
by: Cristina Aguado, et al.
Published: (2014-03-01)