Human CD117 (cKit)+ innate lymphoid cells have a discrete transcriptional profile at homeostasis and are expanded during filarial infection.
Since innate lymphoid cells (ILCs) have been found to play a role in the immune response to helminth parasites in rodents, we sought to determine their role in human helminth infection. By developing multicolor flow cytometry-based methods to identify and enumerate circulating ILCs and their subsets...
Main Authors: | Alexis Boyd, José M C Ribeiro, Thomas B Nutman |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4177898?pdf=render |
Similar Items
-
cKIT Mutations in GISTs and Other Malignancies in Thailand
by: Thongbliew Prempree, et al.
Published: (2006-03-01) -
cKit Lineage Hemogenic Endothelium-Derived Cells Contribute to Mesenteric Lymphatic Vessels
by: Lukas Stanczuk, et al.
Published: (2015-03-01) -
Phosphoproteomic Landscaping Identifies Non-canonical cKIT Signaling in Polycythemia Vera Erythroid Progenitors
by: Giulia Federici, et al.
Published: (2019-11-01) -
Innate Lymphoid Cells in Skin Homeostasis and Malignancy
by: Marek Wagner, et al.
Published: (2021-10-01) -
Microenvironment-Induced Non-sporadic Expression of the AXL and cKIT Receptors Are Related to Epithelial Plasticity and Drug Resistance
by: Tiina A. Jokela, et al.
Published: (2018-04-01)