Skene duct adenocarcinoma in a patient with an elevated serum prostate-specific antigen level: a case report

• Main Authors: Sohgo Tsutsumi, Takashi Kawahara, Yusuke Hattori, Taku Mochizuki, Jun-ichi Teranishi, Kazuhide Makiyama, Yasuhide Miyoshi, Masako Otani, Hiroji Uemura
• Format: Article
• Language: English
• Published: BMC 2018-02-01
• Series: Journal of Medical Case Reports
• Subjects: Prostate-specific antigen; Female genital neoplasm; Skene adenocarcinoma; Urethral adenocarcinoma; Urethral carcinoma
• Online Access: http://link.springer.com/article/10.1186/s13256-017-1558-y

Abstract Background Female urethral carcinoma is a very rare disease that accounts for 0.02% of malignant diseases in female patients. Case presentation A 70-year-old Asian Japanese woman with a urethral tumor was referred to our hospital to undergo further examination. Biopsy specimens showed urethral adenocarcinoma that was positive for prostate-specific antigen. Her serum prostate-specific antigen level before surgery was 34.4 ng/ml. Urethral tumor resection with pelvic lymph node resection was performed. Her serum prostate-specific antigen level decreased to < 0.01 ng/ml after surgery. Conclusions We report a very rare case of Skene duct adenocarcinoma in a female patient with serum prostate-specific antigen elevation.