Pharmaceutical Characterization of MyoNovin, a Novel Skeletal Muscle Regenerator: in silico, in vitro and in vivo Studies

PURPOSE: MyoNovin is a novel skeletal muscle-regenerating compound developed through synthesis of two nitro groups onto a guaifenesin backbone to deliver nitric oxide to skeletal muscle with a potential to treat muscle atrophy. The purpose of this study was to utilize in silico, in vitro, and in vi...

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Main Authors: Samaa Alrushaid, Neal M. Davies, Judy E. Anderson, Tyson Le, Jaime A. Yáñez, Zaid H. Maayah, Ayman O.S. El-Kadi, Ousama Rachid, Casey L. Sayre, Raimar Löbenberg, Frank J. Burczynski
Format: Article
Language:English
Published: Canadian Society for Pharmaceutical Sciences 2018-03-01
Series:Journal of Pharmacy & Pharmaceutical Sciences
Online Access:https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/29683