Potent Dystrophin knock-Down in Vitro and in Vivo Using RNAi Technonlogy and Expression Signature of Myotubes with Dystrophin knocked Down: Attempts at Unravelling the Mystery

Potent Dystrophin knock-Down in Vitro and in Vivo Using RNAi Technonlogy and Expression Signature of Myotubes with Dystrophin knocked Down: Attempts at Unravelling the Mystery

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Duchenne Muscular Dystrophy (DMD) is one of a group of genetically heterogeneous muscular dystrophies that are characterized by progressive weakness and wasting of skeletal muscle. Loss of myofibres occurs in response to a deficiency of dystrophin, a protein which is believed to be responsible for m...

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Bibliographic Details
Main Authors: MM Ghahramani Seno, IR Graham, K Laing, M Pohlschmidt, T Athanasopoulos, MR Crompton, G Dickson
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2005-10-01
Series:Iranian Journal of Public Health
Subjects:
Dsytophin
RNAi
AAV
shRNA
Expression prifiling
Online Access:http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/2496.pdf&manuscript_id=2496

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