Defining therapeutic targets for renal fibrosis: Exploiting the biology of pathogenesis
Renal fibrosis is a failed wound-healing process of the kidney tissue after chronic, sustained injury, which is a common pathway and pathological marker of virtually every type of chronic kidney disease (CKD), regardless of cause. However, there is a lack of effective treatment specifically targetin...
Main Authors: | Hao Yan, Jiangxin Xu, Zhifei Xu, Bo Yang, Peihua Luo, Qiaojun He |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2021-11-01
|
Series: | Biomedicine & Pharmacotherapy |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0753332221008994 |
Similar Items
-
Histone Deacetylase 11 Contributes to Renal Fibrosis by Repressing KLF15 Transcription
by: Lei Mao, et al.
Published: (2020-04-01) -
The Emerging Role of Renal Tubular Epithelial Cells in the Immunological Pathophysiology of Lupus Nephritis
by: Seokchan Hong, et al.
Published: (2020-09-01) -
Ginsenoside Rg1 protects against aging-induced renal interstitial fibrosis due to inhibition of tubular epithelial cells endoplasmic reticulum stress in SAMP8 mice
by: Shixin Ding, et al.
Published: (2020-09-01) -
Role of Akt1 in renal fibrosis and tubular dedifferentiation during the progression of acute kidney injury to chronic kidney disease
by: Il Young Kim, et al.
Published: (2021-07-01) -
Renal Tubule Repair: Is Wnt/β-Catenin a Friend or Foe?
by: Leslie S. Gewin
Published: (2018-01-01)