Intracellular reactive oxygen species determine cancer stem cell radiosensitivity related to predictive biomarker for radiotherapy

Cancer cells display a higher level of reactive oxygen species (ROS) mainly due to increased metabolic activities resulting in altered redox balance. Imbalance in redox arises when the generation of ROS exceeds antioxidants defense system. ROS are generated in cells from multiple pathways, but mitoc...

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Bibliographic Details
Main Author: Kaushala Prasad Mishra
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Journal of Radiation and Cancer Research
Subjects:
Online Access:http://www.journalrcr.org/article.asp?issn=2588-9273;year=2018;volume=9;issue=4;spage=147;epage=154;aulast=Mishra