Intracellular reactive oxygen species determine cancer stem cell radiosensitivity related to predictive biomarker for radiotherapy
Cancer cells display a higher level of reactive oxygen species (ROS) mainly due to increased metabolic activities resulting in altered redox balance. Imbalance in redox arises when the generation of ROS exceeds antioxidants defense system. ROS are generated in cells from multiple pathways, but mitoc...
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Format: | Article |
Language: | English |
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Wolters Kluwer Medknow Publications
2018-01-01
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Series: | Journal of Radiation and Cancer Research |
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Online Access: | http://www.journalrcr.org/article.asp?issn=2588-9273;year=2018;volume=9;issue=4;spage=147;epage=154;aulast=Mishra |