Ischemic Sciatic Neuropathy in a Patient with Liposarcoma

Background Various etiologies are the causative agents for sciatic neuropathy. We present here a case of ischemic sciatic neuropathy in a patient with liposarcoma. Case report A 55-year-old woman presented with severe pain and weakness of the left leg. She had a history of recurred retroperitoneal l...

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Bibliographic Details
Main Authors: Jieun Lee, Jun Hong Lee, Gyu Sik Kim, Min Cheol Park, Naeun Woo, Jeong Hee Cho
Format: Article
Language:English
Published: The Korean Neurocritical Care Society 2017-06-01
Series:Journal of Neurocritical Care
Subjects:
Online Access:http://www.e-jnc.org/upload/pdf/jnc-160100.pdf
Description
Summary:Background Various etiologies are the causative agents for sciatic neuropathy. We present here a case of ischemic sciatic neuropathy in a patient with liposarcoma. Case report A 55-year-old woman presented with severe pain and weakness of the left leg. She had a history of recurred retroperitoneal liposarcoma, and was being administered chemotherapy. Examination revealed weakness in ankle dorsiflexion, plantar flexion and hamstring. Complaints also included dysesthesia, and numbness in the sole and dorsum of the foot. Nerve conduction study showed low compound muscle action potentials and slow motor conduction velocity of left peroneal and tibial nerves, with indiscernible sensory nerve action potentials of the left superficial peroneal and sural nerves. Computed tomography angiography revealed occlusion of the left common iliac artery. Commencement of intravenous infusion of heparin resulted in skin color change and progression of the weakness. Hence, the patient underwent an emergency thrombectomy. Conclusions Ischemia should be considered as a cause of sciatic neuropathy in cancer patients, which requires management with timely treatment.
ISSN:2005-0348
2508-1349