The CDKN2A G500 allele is more frequent in GBM patients with no defined telomere maintenance mechanism tumors and is associated with poorer survival.

The CDKN2A G500 allele is more frequent in GBM patients with no defined telomere maintenance mechanism tumors and is associated with poorer survival.

Prognostic markers for glioblastoma multiforme (GBM) are important for patient management. Recent advances have identified prognostic markers for GBMs that use telomerase or the alternative lengthening of telomeres (ALT) mechanism for telomere maintenance. Approximately 40% of GBMs have no defined t...

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Bibliographic Details
Main Authors: Janice A Royds, Shafagh Al Nadaf, Anna K Wiles, Yu-Jen Chen, Antonio Ahn, Alisha Shaw, Sara Bowie, Frederic Lam, Bruce C Baguley, Antony W Braithwaite, Martin R MacFarlane, Noelyn A Hung, Tania L Slatter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3202568?pdf=render

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