Tdp1 Inhibition as a Promising Approach to New Anticancer Drugs
The cytotoxic effects of chemotherapy and radiation that are clinically used to treat malignancies are directly related to their propensity to generate DNA damage. [...]
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MDPI AG
2019-08-01
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| Series: | Proceedings |
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| Online Access: | https://www.mdpi.com/2504-3900/22/1/35 |
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doaj-e8e7ddaa6d254a9ea6a5baeefc7444ac2020-11-24T21:34:18ZengMDPI AGProceedings2504-39002019-08-012213510.3390/proceedings2019022035proceedings2019022035Tdp1 Inhibition as a Promising Approach to New Anticancer DrugsKonstantin Volcho0Alexandra Zakharenko1Olga Luzina2Tatyana Khomenko3Evgeniy Suslov4Oksana Salomatina5Olga Zakharova6Nikolai Li-Zhulanov7Jóhannes Reynisson8Olga Lavrik9Nariman Salakhutdinov10Novosibirsk Institute of Organic Chemistry, Novosibirsk 630090, RussiaNovosibirsk Institute of Chemical Biology and Fundamental Medicine, Novosibirsk 630090, RussiaNovosibirsk Institute of Organic Chemistry, Novosibirsk 630090, RussiaNovosibirsk Institute of Organic Chemistry, Novosibirsk 630090, RussiaNovosibirsk Institute of Organic Chemistry, Novosibirsk 630090, RussiaNovosibirsk Institute of Organic Chemistry, Novosibirsk 630090, RussiaNovosibirsk Institute of Chemical Biology and Fundamental Medicine, Novosibirsk 630090, RussiaNovosibirsk Institute of Organic Chemistry, Novosibirsk 630090, RussiaSchool of Chemical Sciences, University of Auckland, Auckland 1142, New ZealandNovosibirsk Institute of Chemical Biology and Fundamental Medicine, Novosibirsk 630090, RussiaNovosibirsk Institute of Organic Chemistry, Novosibirsk 630090, RussiaThe cytotoxic effects of chemotherapy and radiation that are clinically used to treat malignancies are directly related to their propensity to generate DNA damage. [...]https://www.mdpi.com/2504-3900/22/1/35anticancer agentTdp1 inhibitorDNA repair enzymesynthesisusnic acidpentathiepineadamantanemolecular modelingterpenecoumarin |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Konstantin Volcho Alexandra Zakharenko Olga Luzina Tatyana Khomenko Evgeniy Suslov Oksana Salomatina Olga Zakharova Nikolai Li-Zhulanov Jóhannes Reynisson Olga Lavrik Nariman Salakhutdinov |
| spellingShingle |
Konstantin Volcho Alexandra Zakharenko Olga Luzina Tatyana Khomenko Evgeniy Suslov Oksana Salomatina Olga Zakharova Nikolai Li-Zhulanov Jóhannes Reynisson Olga Lavrik Nariman Salakhutdinov Tdp1 Inhibition as a Promising Approach to New Anticancer Drugs Proceedings anticancer agent Tdp1 inhibitor DNA repair enzyme synthesis usnic acid pentathiepine adamantane molecular modeling terpene coumarin |
| author_facet |
Konstantin Volcho Alexandra Zakharenko Olga Luzina Tatyana Khomenko Evgeniy Suslov Oksana Salomatina Olga Zakharova Nikolai Li-Zhulanov Jóhannes Reynisson Olga Lavrik Nariman Salakhutdinov |
| author_sort |
Konstantin Volcho |
| title |
Tdp1 Inhibition as a Promising Approach to New Anticancer Drugs |
| title_short |
Tdp1 Inhibition as a Promising Approach to New Anticancer Drugs |
| title_full |
Tdp1 Inhibition as a Promising Approach to New Anticancer Drugs |
| title_fullStr |
Tdp1 Inhibition as a Promising Approach to New Anticancer Drugs |
| title_full_unstemmed |
Tdp1 Inhibition as a Promising Approach to New Anticancer Drugs |
| title_sort |
tdp1 inhibition as a promising approach to new anticancer drugs |
| publisher |
MDPI AG |
| series |
Proceedings |
| issn |
2504-3900 |
| publishDate |
2019-08-01 |
| description |
The cytotoxic effects of chemotherapy and radiation that are clinically used to treat malignancies are directly related to their propensity to generate DNA damage. [...] |
| topic |
anticancer agent Tdp1 inhibitor DNA repair enzyme synthesis usnic acid pentathiepine adamantane molecular modeling terpene coumarin |
| url |
https://www.mdpi.com/2504-3900/22/1/35 |
| work_keys_str_mv |
AT konstantinvolcho tdp1inhibitionasapromisingapproachtonewanticancerdrugs AT alexandrazakharenko tdp1inhibitionasapromisingapproachtonewanticancerdrugs AT olgaluzina tdp1inhibitionasapromisingapproachtonewanticancerdrugs AT tatyanakhomenko tdp1inhibitionasapromisingapproachtonewanticancerdrugs AT evgeniysuslov tdp1inhibitionasapromisingapproachtonewanticancerdrugs AT oksanasalomatina tdp1inhibitionasapromisingapproachtonewanticancerdrugs AT olgazakharova tdp1inhibitionasapromisingapproachtonewanticancerdrugs AT nikolailizhulanov tdp1inhibitionasapromisingapproachtonewanticancerdrugs AT johannesreynisson tdp1inhibitionasapromisingapproachtonewanticancerdrugs AT olgalavrik tdp1inhibitionasapromisingapproachtonewanticancerdrugs AT narimansalakhutdinov tdp1inhibitionasapromisingapproachtonewanticancerdrugs |
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1725950064200777728 |