Neurokinin-1 Receptor Antagonist Treatment in Polymicrobial Sepsis: Molecular Insights

Neurokinin-1 receptor blocking has been shown to be beneficial against lung injury in polymicrobial sepsis. In this paper, we evaluated the possible mediators and the mechanism involved. Mice were subjected to cecal ligation and puncture (CLP-) induced sepsis or sham surgery. Vehicle or SR140333 [1 ...

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Bibliographic Details
Main Authors: Akhil Hegde, Yung-Hua Koh, Shabbir M. Moochhala, Madhav Bhatia
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:International Journal of Inflammation
Online Access:http://dx.doi.org/10.4061/2010/601098

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