Phenotypic and Molecular Convergence of 2q23.1 Deletion Syndrome with Other Neurodevelopmental Syndromes Associated with Autism Spectrum Disorder

Phenotypic and Molecular Convergence of 2q23.1 Deletion Syndrome with Other Neurodevelopmental Syndromes Associated with Autism Spectrum Disorder

Roughly 20% of autism spectrum disorders (ASD) are syndromic with a well-established genetic cause. Studying the genes involved can provide insight into the molecular and cellular mechanisms of ASD. 2q23.1 deletion syndrome (causative gene, MBD5) is a recently identified genetic neurodevelopmental...

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Bibliographic Details
Main Authors: Sureni V. Mullegama, Joseph T. Alaimo, Li Chen, Sarah H. Elsea
Format: Article
Language:English
Published: MDPI AG 2015-04-01
Series:International Journal of Molecular Sciences
Subjects:
MBD5
ASD
networks
overlapping phenotypes
UBE3A
TCF4
MEF2C
EHMT1
RAI1
transcriptional regulation
pathways
network analysis
Online Access:http://www.mdpi.com/1422-0067/16/4/7627

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http://www.mdpi.com/1422-0067/16/4/7627

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