Towards precision quantification of contamination in metagenomic sequencing experiments

Towards precision quantification of contamination in metagenomic sequencing experiments

Abstract Metagenomic next-generation sequencing (mNGS) experiments involving small amounts of nucleic acid input are highly susceptible to erroneous conclusions resulting from unintentional sequencing of occult contaminants, especially those derived from molecular biology reagents. Recent work sugge...

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Bibliographic Details
Main Authors: M. S. Zinter, M. Y. Mayday, K. K. Ryckman, L. L. Jelliffe-Pawlowski, J. L. DeRisi
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Microbiome
Subjects:
Metagenomics
Sequence analysis
DNA
DNA contamination
Regression analysis
Microbiota
Online Access:http://link.springer.com/article/10.1186/s40168-019-0678-6

Internet

http://link.springer.com/article/10.1186/s40168-019-0678-6

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