Gene clustering and copy number variation in alkaloid metabolic pathways of opium poppy
The opium poppy has been a source of painkilling drugs synthesized by the benzylisoquinoline alkaloid pathway. Here, the authors report an improved genome assembly and reveal gene clustering and copy number variation in alkaloid metabolic pathways.
Main Authors: | , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2020-03-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-15040-2 |
id |
doaj-e91dc3f830b242d7bc6f05c17604aa7b |
---|---|
record_format |
Article |
spelling |
doaj-e91dc3f830b242d7bc6f05c17604aa7b2021-05-11T08:09:18ZengNature Publishing GroupNature Communications2041-17232020-03-0111111310.1038/s41467-020-15040-2Gene clustering and copy number variation in alkaloid metabolic pathways of opium poppyQiushi Li0Sukanya Ramasamy1Pooja Singh2Jillian M. Hagel3Sonja M. Dunemann4Xue Chen5Rongji Chen6Lisa Yu7Joseph E. Tucker8Peter J. Facchini9Sam Yeaman10Department of Biological Sciences, University of CalgaryDepartment of Biological Sciences, University of CalgaryDepartment of Biological Sciences, University of CalgaryDepartment of Biological Sciences, University of CalgaryDepartment of Ecosystem and Public Health, University of CalgaryDepartment of Biological Sciences, University of CalgaryDepartment of Biological Sciences, University of CalgaryDepartment of Biological Sciences, University of CalgaryWillow Biosciences Inc.Department of Biological Sciences, University of CalgaryDepartment of Biological Sciences, University of CalgaryThe opium poppy has been a source of painkilling drugs synthesized by the benzylisoquinoline alkaloid pathway. Here, the authors report an improved genome assembly and reveal gene clustering and copy number variation in alkaloid metabolic pathways.https://doi.org/10.1038/s41467-020-15040-2 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Qiushi Li Sukanya Ramasamy Pooja Singh Jillian M. Hagel Sonja M. Dunemann Xue Chen Rongji Chen Lisa Yu Joseph E. Tucker Peter J. Facchini Sam Yeaman |
spellingShingle |
Qiushi Li Sukanya Ramasamy Pooja Singh Jillian M. Hagel Sonja M. Dunemann Xue Chen Rongji Chen Lisa Yu Joseph E. Tucker Peter J. Facchini Sam Yeaman Gene clustering and copy number variation in alkaloid metabolic pathways of opium poppy Nature Communications |
author_facet |
Qiushi Li Sukanya Ramasamy Pooja Singh Jillian M. Hagel Sonja M. Dunemann Xue Chen Rongji Chen Lisa Yu Joseph E. Tucker Peter J. Facchini Sam Yeaman |
author_sort |
Qiushi Li |
title |
Gene clustering and copy number variation in alkaloid metabolic pathways of opium poppy |
title_short |
Gene clustering and copy number variation in alkaloid metabolic pathways of opium poppy |
title_full |
Gene clustering and copy number variation in alkaloid metabolic pathways of opium poppy |
title_fullStr |
Gene clustering and copy number variation in alkaloid metabolic pathways of opium poppy |
title_full_unstemmed |
Gene clustering and copy number variation in alkaloid metabolic pathways of opium poppy |
title_sort |
gene clustering and copy number variation in alkaloid metabolic pathways of opium poppy |
publisher |
Nature Publishing Group |
series |
Nature Communications |
issn |
2041-1723 |
publishDate |
2020-03-01 |
description |
The opium poppy has been a source of painkilling drugs synthesized by the benzylisoquinoline alkaloid pathway. Here, the authors report an improved genome assembly and reveal gene clustering and copy number variation in alkaloid metabolic pathways. |
url |
https://doi.org/10.1038/s41467-020-15040-2 |
work_keys_str_mv |
AT qiushili geneclusteringandcopynumbervariationinalkaloidmetabolicpathwaysofopiumpoppy AT sukanyaramasamy geneclusteringandcopynumbervariationinalkaloidmetabolicpathwaysofopiumpoppy AT poojasingh geneclusteringandcopynumbervariationinalkaloidmetabolicpathwaysofopiumpoppy AT jillianmhagel geneclusteringandcopynumbervariationinalkaloidmetabolicpathwaysofopiumpoppy AT sonjamdunemann geneclusteringandcopynumbervariationinalkaloidmetabolicpathwaysofopiumpoppy AT xuechen geneclusteringandcopynumbervariationinalkaloidmetabolicpathwaysofopiumpoppy AT rongjichen geneclusteringandcopynumbervariationinalkaloidmetabolicpathwaysofopiumpoppy AT lisayu geneclusteringandcopynumbervariationinalkaloidmetabolicpathwaysofopiumpoppy AT josephetucker geneclusteringandcopynumbervariationinalkaloidmetabolicpathwaysofopiumpoppy AT peterjfacchini geneclusteringandcopynumbervariationinalkaloidmetabolicpathwaysofopiumpoppy AT samyeaman geneclusteringandcopynumbervariationinalkaloidmetabolicpathwaysofopiumpoppy |
_version_ |
1721451095305224192 |