The Impact of Variant Allele Frequency in EGFR Mutated NSCLC Patients on Targeted Therapy

The Impact of Variant Allele Frequency in EGFR Mutated NSCLC Patients on Targeted Therapy

EGFR mutations represent the most common currently targetable oncogenic driver in non-small cell lung cancer. There has been tremendous progress in targeting this alteration over the course of the last decade, and third generation tyrosine kinase inhibitors offer previously unseen survival rates amo...

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Bibliographic Details
Main Authors: Alex Friedlaender, Petros Tsantoulis, Mathieu Chevallier, Claudio De Vito, Alfredo Addeo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Oncology
Subjects:
TKI
allele frequency
EGFR
NSCLC
VAF
allelic frequency
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.644472/full

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