Quantitative determination of imatinib stability under various stress conditions

Quantitative determination of imatinib stability under various stress conditions

Objective: A simple, rapid, reverse phase and stability-indicating high-performance liquid chromatography (HPLC) method for the estimation of imatinib in solution and in plasma under forced degradation conditions was developed. Materials and Methods: The method employed isocratic elution using a Wat...

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Bibliographic Details
Main Authors: Khalid Mohammed Alkharfy, Rao Muzaffer Ali Khan, Majed Al-Asmari, Baderelddin Hashim Alhadeyah, Ajaz Ahmad
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2013-01-01
Series:Journal of Pharmacy and Bioallied Sciences
Subjects:
HPLC
imatinib
method validation
stability indicating
Online Access:http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2013;volume=5;issue=1;spage=49;epage=52;aulast=Alkharfy

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