Propafenone efficacy in treatment of atrial fibrillation paroxysms: a placebo-controlled study

In a placebo-controlled study, propafenone efficacy and safety for pharmaceutical cardioversion in atrial fibrillation (AF) paroxysms were studied. The study included 50 patients aged 28-69 years (mean age 53,9+9,7), with AF paroxysms lasting for less than 48 hours. Participants were randomized to p...

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Main Authors: Yu. A. Bunin, L. K. Anfalova
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC  2005-12-01
Series:Российский кардиологический журнал
Subjects:
Online Access:https://russjcardiol.elpub.ru/jour/article/view/2343
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spelling doaj-e9a135cf00344fe6a7c80ecb8a27bf692021-07-28T14:02:07Zrus«FIRMA «SILICEA» LLC Российский кардиологический журнал1560-40712618-76202005-12-010657612089Propafenone efficacy in treatment of atrial fibrillation paroxysms: a placebo-controlled studyYu. A. Bunin0L. K. Anfalova1Российская медицинская академия последипломного образованияРоссийская медицинская академия последипломного образованияIn a placebo-controlled study, propafenone efficacy and safety for pharmaceutical cardioversion in atrial fibrillation (AF) paroxysms were studied. The study included 50 patients aged 28-69 years (mean age 53,9+9,7), with AF paroxysms lasting for less than 48 hours. Participants were randomized to propafenone (single dose of 600 mg, per os) or placebo. Eight hours later, sinus rhythm was restored in propafenone group more effectively than in placebo group: 85,7% and 33,3%, respectively (p=0,001). Mean sinus rhythm restoring time was 2,5+1,9 and 3,8+1,5 hours, respectively.https://russjcardiol.elpub.ru/jour/article/view/2343atrial fibrillationcardioversionpropafenone
collection DOAJ
language Russian
format Article
sources DOAJ
author Yu. A. Bunin
L. K. Anfalova
spellingShingle Yu. A. Bunin
L. K. Anfalova
Propafenone efficacy in treatment of atrial fibrillation paroxysms: a placebo-controlled study
Российский кардиологический журнал
atrial fibrillation
cardioversion
propafenone
author_facet Yu. A. Bunin
L. K. Anfalova
author_sort Yu. A. Bunin
title Propafenone efficacy in treatment of atrial fibrillation paroxysms: a placebo-controlled study
title_short Propafenone efficacy in treatment of atrial fibrillation paroxysms: a placebo-controlled study
title_full Propafenone efficacy in treatment of atrial fibrillation paroxysms: a placebo-controlled study
title_fullStr Propafenone efficacy in treatment of atrial fibrillation paroxysms: a placebo-controlled study
title_full_unstemmed Propafenone efficacy in treatment of atrial fibrillation paroxysms: a placebo-controlled study
title_sort propafenone efficacy in treatment of atrial fibrillation paroxysms: a placebo-controlled study
publisher «FIRMA «SILICEA» LLC 
series Российский кардиологический журнал
issn 1560-4071
2618-7620
publishDate 2005-12-01
description In a placebo-controlled study, propafenone efficacy and safety for pharmaceutical cardioversion in atrial fibrillation (AF) paroxysms were studied. The study included 50 patients aged 28-69 years (mean age 53,9+9,7), with AF paroxysms lasting for less than 48 hours. Participants were randomized to propafenone (single dose of 600 mg, per os) or placebo. Eight hours later, sinus rhythm was restored in propafenone group more effectively than in placebo group: 85,7% and 33,3%, respectively (p=0,001). Mean sinus rhythm restoring time was 2,5+1,9 and 3,8+1,5 hours, respectively.
topic atrial fibrillation
cardioversion
propafenone
url https://russjcardiol.elpub.ru/jour/article/view/2343
work_keys_str_mv AT yuabunin propafenoneefficacyintreatmentofatrialfibrillationparoxysmsaplacebocontrolledstudy
AT lkanfalova propafenoneefficacyintreatmentofatrialfibrillationparoxysmsaplacebocontrolledstudy
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