High prevalence of <it>dhfr </it>triple mutant and correlation with high rates of sulphadoxine-pyrimethamine treatment failures <it>in vivo </it>in Gabonese children

High prevalence of <it>dhfr </it>triple mutant and correlation with high rates of sulphadoxine-pyrimethamine treatment failures <it>in vivo </it>in Gabonese children

<p>Abstract</p> <p>Background</p> <p>Drug resistance contributes to the global malaria burden. <it>Plasmodium </it><it>falciparum </it>dihydrofolate reductase (<it>dhfr</it>) and dihydropteroate synthase (<it>dhps</it>) po...

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Main Authors: Profanter Katharina, Greutélaers Katja C, Gabor Julian J, Ord Rosalynn, Oyakhirome Sunny, Mombo-Ngoma Ghyslain, Greutélaers Benedikt, Kurth Florian, Lell Bertrand, Kun Jürgen FJ, Issifou Saadou, Roper Cally, Kremsner Peter G, Grobusch Martin P
Format: Article
Language:English
Published: BMC 2011-05-01
Series:Malaria Journal
Online Access:http://www.malariajournal.com/content/10/1/123

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