A Novel Highly Sensitive Method for Measuring Inflammatory Neural-Derived APC Activity in Glial Cell Lines, Mouse Brain and Human CSF
Background: Neural inflammation is linked to coagulation. Low levels of thrombin have a neuroprotective effect, mediated by activated protein C (APC). We describe a sensitive novel method for the measurement of APC activity at the low concentrations found in neural tissue. Methods: APC activity was...
Main Authors: | Valery Golderman, Shany G. Gofrit, Nicola Maggio, Orna Gera, Alexandra Gerasimov, Dar Laks, Joab Chapman, Efrat Shavit-Stein |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-03-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/21/7/2422 |
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