Functions and Epigenetic Regulation of Wwox in Bone Metastasis from Breast Carcinoma: Comparison with Primary Tumors

Functions and Epigenetic Regulation of Wwox in Bone Metastasis from Breast Carcinoma: Comparison with Primary Tumors

Epigenetic mechanisms influence molecular patterns important for the bone-metastatic process, and here we highlight the role of WW-domain containing oxidoreductase (Wwox). The tumor-suppressor Wwox lacks in almost all cancer types; the variable expression in osteosarcomas is related to lung-metastas...

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Bibliographic Details
Main Authors:	Paola Maroni, Emanuela Matteucci, Paola Bendinelli, Maria Alfonsina Desiderio
Format:	Article
Language:	English
Published:	MDPI AG 2017-01-01
Series:	International Journal of Molecular Sciences
Subjects:	bone metastasis epigenetic reprogramming Wwox transcription factors
Online Access:	http://www.mdpi.com/1422-0067/18/1/75

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