An <i>O</i>-GlcNAcylomic Approach Reveals ACLY as a Potential Target in Sepsis in the Young Rat

An <i>O</i>-GlcNAcylomic Approach Reveals ACLY as a Potential Target in Sepsis in the Young Rat

Sepsis in the young population, which is particularly at risk, is rarely studied. <i>O</i>-GlcNAcylation is a post-translational modification involved in cell survival, stress response and metabolic regulation. <i>O</i>-GlcNAc stimulation is beneficial in adult septic rats. T...

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Bibliographic Details
Main Authors: Manon Denis, Thomas Dupas, Antoine Persello, Justine Dontaine, Laurent Bultot, Charlotte Betus, Thomas Pelé, Justine Dhot, Angélique Erraud, Anaïs Maillard, Jérôme Montnach, Aurélia A. Leroux, Edith Bigot-Corbel, Didier Vertommen, Matthieu Rivière, Jacques Lebreton, Arnaud Tessier, Michel De Waard, Luc Bertrand, Bertrand Rozec, Benjamin Lauzier
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
<i>O</i>-GlcNAcylation
septic shock
children
mass spectrometry
<i>O</i>-GlcNAcylomics
Online Access:https://www.mdpi.com/1422-0067/22/17/9236

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