Isolated Limb Perfusion With Melphalan Triggers Immune Activation in Melanoma Patients

Isolated Limb Perfusion With Melphalan Triggers Immune Activation in Melanoma Patients

Hyperthermic isolated limb perfusion with melphalan (M-ILP) is a treatment option for melanoma patients with metastases confined to the limbs. This study aimed at defining the role of cellular immunity for the clinical response to M-ILP in melanoma patients. It was observed that patients with enhanc...

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Bibliographic Details
Main Authors: Junko Johansson, Roberta Kiffin, Annica Andersson, Per Lindnér, Peter L. Naredi, Roger Olofsson Bagge, Anna Martner
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Oncology
Subjects:
melanoma
isolated limb perfusion
melphalan
monocytes
cytotoxic T cells
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2018.00570/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2018.00570/full

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