Dysregulation of the autophagic-lysosomal pathway in Gaucher and Parkinson's disease
The finding that mutations in the Gaucher's Disease (GD) gene GBA1 are a strong risk factor for Parkinson's Disease (PD) has allowed for unique insights into pathophysiology centered on disruption of the autophagic-lysosomal pathway. Protein aggregations in the form of Lewy bodies and the...
Main Authors: | Caleb Pitcairn, Willayat Yousuf Wani, Joseph R. Mazzulli |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-02-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996118300743 |
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