AMPA receptor activation causes silencing of AMPA receptor-mediated synaptic transmission in the developing hippocampus.

AMPA receptor activation causes silencing of AMPA receptor-mediated synaptic transmission in the developing hippocampus.

Agonist-induced internalization of transmembrane receptors is a widespread biological phenomenon that also may serve as a mechanism for synaptic plasticity. Here we show that the agonist AMPA causes a depression of AMPA receptor (AMPAR) signaling at glutamate synapses in the CA1 region of the hippoc...

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Bibliographic Details
Main Authors: Pontus Wasling, Joakim Strandberg, Eric Hanse
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3317613?pdf=render

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