Acute schistosomiasis mansoni: revisited and reconsidered
Acute schistosomiasis is a systemic hypersensitivity reaction against the migrating schistosomula and eggs. A variety of clinical manifestations appear during the migration of schistosomes in humans: cercarial dermatitis, fever, pneumonia, diarrhoea, hepatomegaly, splenomegaly, skin lesions, liver a...
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Instituto Oswaldo Cruz, Ministério da Saúde
2010-07-01
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doaj-ea137c220fe2434c9939a50c728bf0282020-11-25T01:07:32ZengInstituto Oswaldo Cruz, Ministério da SaúdeMemórias do Instituto Oswaldo Cruz.0074-02761678-80602010-07-01105442243510.1590/S0074-02762010000400012Acute schistosomiasis mansoni: revisited and reconsideredJosé Roberto LambertucciAcute schistosomiasis is a systemic hypersensitivity reaction against the migrating schistosomula and eggs. A variety of clinical manifestations appear during the migration of schistosomes in humans: cercarial dermatitis, fever, pneumonia, diarrhoea, hepatomegaly, splenomegaly, skin lesions, liver abscesses, brain tumours and myeloradiculopathy. Hypereosinophilia is common and aids diagnosis. The disease has been overlooked, misdiagnosed, underestimated and underreported in endemic areas, but risk groups are well known, including military recruits, some religious congregations, rural tourists and people practicing recreational water sports. Serology may help in diagnosis, but the finding of necrotic-exudative granulomata in a liver biopsy specimen is pathognomonic. Differentials include malaria, tuberculosis, typhoid fever, kala-azar, prolonged Salmonella bacteraemia, lymphoma, toxocariasis, liver abscesses and fever of undetermined origin. For symptomatic hospitalised patients, treatment with steroids and schistosomicides is recommended. Treatment is curative in those timely diagnosed.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762010000400012acute schistosomiasiscercarial dermatitisFUOdermatitisneuroschistosomiasispyogenic liver abscesses |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
José Roberto Lambertucci |
spellingShingle |
José Roberto Lambertucci Acute schistosomiasis mansoni: revisited and reconsidered Memórias do Instituto Oswaldo Cruz. acute schistosomiasis cercarial dermatitis FUO dermatitis neuroschistosomiasis pyogenic liver abscesses |
author_facet |
José Roberto Lambertucci |
author_sort |
José Roberto Lambertucci |
title |
Acute schistosomiasis mansoni: revisited and reconsidered |
title_short |
Acute schistosomiasis mansoni: revisited and reconsidered |
title_full |
Acute schistosomiasis mansoni: revisited and reconsidered |
title_fullStr |
Acute schistosomiasis mansoni: revisited and reconsidered |
title_full_unstemmed |
Acute schistosomiasis mansoni: revisited and reconsidered |
title_sort |
acute schistosomiasis mansoni: revisited and reconsidered |
publisher |
Instituto Oswaldo Cruz, Ministério da Saúde |
series |
Memórias do Instituto Oswaldo Cruz. |
issn |
0074-0276 1678-8060 |
publishDate |
2010-07-01 |
description |
Acute schistosomiasis is a systemic hypersensitivity reaction against the migrating schistosomula and eggs. A variety of clinical manifestations appear during the migration of schistosomes in humans: cercarial dermatitis, fever, pneumonia, diarrhoea, hepatomegaly, splenomegaly, skin lesions, liver abscesses, brain tumours and myeloradiculopathy. Hypereosinophilia is common and aids diagnosis. The disease has been overlooked, misdiagnosed, underestimated and underreported in endemic areas, but risk groups are well known, including military recruits, some religious congregations, rural tourists and people practicing recreational water sports. Serology may help in diagnosis, but the finding of necrotic-exudative granulomata in a liver biopsy specimen is pathognomonic. Differentials include malaria, tuberculosis, typhoid fever, kala-azar, prolonged Salmonella bacteraemia, lymphoma, toxocariasis, liver abscesses and fever of undetermined origin. For symptomatic hospitalised patients, treatment with steroids and schistosomicides is recommended. Treatment is curative in those timely diagnosed. |
topic |
acute schistosomiasis cercarial dermatitis FUO dermatitis neuroschistosomiasis pyogenic liver abscesses |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762010000400012 |
work_keys_str_mv |
AT joserobertolambertucci acuteschistosomiasismansonirevisitedandreconsidered |
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