Crystal Structure of a 9-Subunit Archaeal Exosome in Pre-Catalytic States of the Phosphorolytic Reaction

The RNA exosome is an important protein complex that functions in the 3′ processing and degradation of RNA in archaeal and eukaryotic organisms. The archaeal exosome is functionally similar to bacterial polynucleotide phosphorylase (PNPase) and RNase PH enzymes as it uses inorganic phosphate (Pi) to...

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Bibliographic Details
Main Authors: Esben Lorentzen, Elena Conti
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Archaea
Online Access:http://dx.doi.org/10.1155/2012/721869