Selection of chemical markers for the quality control of medicinal plants of the genus Cecropia
Context: Several Cecropia (Cecropiaceae) species are traditionally used in Latin America for the treatment of a variety of diseases including diabetes, arterial hypertension, asthma, bronchitis, anxiety, and inflammation. At present, a number of commercial products based on these plants have been in...
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doaj-ea26296c51864b49aadbda714b2c5fcc2020-11-25T03:11:29ZengTaylor & Francis GroupPharmaceutical Biology1388-02091744-51162017-01-015511500151210.1080/13880209.2017.13074211307421Selection of chemical markers for the quality control of medicinal plants of the genus CecropiaAndrés Rivera-Mondragón0Orlando O. Ortíz1Sebastiaan Bijttebier2Arnold Vlietinck3Sandra Apers4Luc Pieters5Catherina Caballero-George6University of AntwerpUniversidad de Panamá, Estafeta UniversitariaUniversity of AntwerpUniversity of AntwerpUniversity of AntwerpUniversity of AntwerpInstitute of Scientific Research and High Technology Services (INDICASAT-AIP)Context: Several Cecropia (Cecropiaceae) species are traditionally used in Latin America for the treatment of a variety of diseases including diabetes, arterial hypertension, asthma, bronchitis, anxiety, and inflammation. At present, a number of commercial products based on these plants have been introduced into the market with very little information on methods for guaranteeing their quality and safety. Objective: This work proposes potential chemical markers for the quality control of the raw materials of Cecropia obtusifolia Bertol., Cecropia peltata L., Cecropia glaziovii Snethl., Cecropia pachystachya Trécul, and Cecropia hololeuca Miq. Methods: The Herbal Chemical Marker Ranking System (Herb MaRS) developed by the National Institute of Complementary Medicine (NICM) at the University of Western Sydney was used for selecting chemical markers for the quality control of selected medicinal species of Cecropia. This review covers the period from 1982 to 2016. Results: Chlorogenic acid, flavonoidal glycosides (orientin, isoorientin, vitexin, isovitexin, and rutin), catechin, epicatechin, procyanidins (B2, B5, and C1), steroids (β-sitosterol), and triterpenoids (α-amyrin, pomolic, tormentic and ursolic acids) were selected as chemical markers for the quality control of the leaves. Conclusion: It is necessary to establish comprehensive standards for guaranteeing quality, safety and efficacy of herbal drugs. The selection of adequate chemical markers for quality control purposes requires a good knowledge about the chemical composition of medicinal plants and their associated biological properties. To the best of our knowledge this review article is the first to address the identification and quantitative determination of the chemical markers for the genus Cecropia.http://dx.doi.org/10.1080/13880209.2017.1307421urticaceaeherbal medicinequality control |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Andrés Rivera-Mondragón Orlando O. Ortíz Sebastiaan Bijttebier Arnold Vlietinck Sandra Apers Luc Pieters Catherina Caballero-George |
spellingShingle |
Andrés Rivera-Mondragón Orlando O. Ortíz Sebastiaan Bijttebier Arnold Vlietinck Sandra Apers Luc Pieters Catherina Caballero-George Selection of chemical markers for the quality control of medicinal plants of the genus Cecropia Pharmaceutical Biology urticaceae herbal medicine quality control |
author_facet |
Andrés Rivera-Mondragón Orlando O. Ortíz Sebastiaan Bijttebier Arnold Vlietinck Sandra Apers Luc Pieters Catherina Caballero-George |
author_sort |
Andrés Rivera-Mondragón |
title |
Selection of chemical markers for the quality control of medicinal plants of the genus Cecropia |
title_short |
Selection of chemical markers for the quality control of medicinal plants of the genus Cecropia |
title_full |
Selection of chemical markers for the quality control of medicinal plants of the genus Cecropia |
title_fullStr |
Selection of chemical markers for the quality control of medicinal plants of the genus Cecropia |
title_full_unstemmed |
Selection of chemical markers for the quality control of medicinal plants of the genus Cecropia |
title_sort |
selection of chemical markers for the quality control of medicinal plants of the genus cecropia |
publisher |
Taylor & Francis Group |
series |
Pharmaceutical Biology |
issn |
1388-0209 1744-5116 |
publishDate |
2017-01-01 |
description |
Context: Several Cecropia (Cecropiaceae) species are traditionally used in Latin America for the treatment of a variety of diseases including diabetes, arterial hypertension, asthma, bronchitis, anxiety, and inflammation. At present, a number of commercial products based on these plants have been introduced into the market with very little information on methods for guaranteeing their quality and safety. Objective: This work proposes potential chemical markers for the quality control of the raw materials of Cecropia obtusifolia Bertol., Cecropia peltata L., Cecropia glaziovii Snethl., Cecropia pachystachya Trécul, and Cecropia hololeuca Miq. Methods: The Herbal Chemical Marker Ranking System (Herb MaRS) developed by the National Institute of Complementary Medicine (NICM) at the University of Western Sydney was used for selecting chemical markers for the quality control of selected medicinal species of Cecropia. This review covers the period from 1982 to 2016. Results: Chlorogenic acid, flavonoidal glycosides (orientin, isoorientin, vitexin, isovitexin, and rutin), catechin, epicatechin, procyanidins (B2, B5, and C1), steroids (β-sitosterol), and triterpenoids (α-amyrin, pomolic, tormentic and ursolic acids) were selected as chemical markers for the quality control of the leaves. Conclusion: It is necessary to establish comprehensive standards for guaranteeing quality, safety and efficacy of herbal drugs. The selection of adequate chemical markers for quality control purposes requires a good knowledge about the chemical composition of medicinal plants and their associated biological properties. To the best of our knowledge this review article is the first to address the identification and quantitative determination of the chemical markers for the genus Cecropia. |
topic |
urticaceae herbal medicine quality control |
url |
http://dx.doi.org/10.1080/13880209.2017.1307421 |
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