The Biophysical Interaction of the Danger-Associated Molecular Pattern (DAMP) Calreticulin with the Pattern-Associated Molecular Pattern (PAMP) Lipopolysaccharide

The Biophysical Interaction of the Danger-Associated Molecular Pattern (DAMP) Calreticulin with the Pattern-Associated Molecular Pattern (PAMP) Lipopolysaccharide

The endoplasmic reticulum (ER) chaperone protein, calreticulin (CRT), is essential for proper glycoprotein folding and maintaining cellular calcium homeostasis. During ER stress, CRT is overexpressed as part of the unfolded protein response (UPR). In addition, CRT can be released as a damage-associa...

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Bibliographic Details
Main Authors:	Unnati M. Pandya, Chinaza Egbuta, Trefa M. Abdullah Norman, Chih-Yuan (Edward) Chiang, Valerie R. Wiersma, Rekha G. Panchal, Edwin Bremer, Paul Eggleton, Leslie I Gold
Format:	Article
Language:	English
Published:	MDPI AG 2019-01-01
Series:	International Journal of Molecular Sciences
Subjects:	calreticulin endoplasmic reticulum chaperone innate immunity lipopolysaccharide Danger Associated Molecular Patterns (DAMPs) Pathogen Associated Molecular Patterns (PAMPs) bacterial opsonin
Online Access:	http://www.mdpi.com/1422-0067/20/2/408

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