Gambogic acid inhibits LPS-induced macrophage pro-inflammatory cytokine production mainly through suppression of the p38 pathway

Gambogic acid inhibits LPS-induced macrophage pro-inflammatory cytokine production mainly through suppression of the p38 pathway

Objective(s): In traditional Chinese medicine, gamboge can detoxify bodies, kill parasites, and act as a hemostatic agent. Recent studies have demonstrated that gambogic acid (GBA) suppressed inflammation in arthritis, and also presented antitumor effect. Thus, this study investigated the new biolog...

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Bibliographic Details
Main Authors:	Ma Jianjun, Kangmao Huang, Yan Ma, Shuai Chen, Chao Liu, Zhi Shan, Xiangqian Fang
Format:	Article
Language:	English
Published:	Mashhad University of Medical Sciences 2018-07-01
Series:	Iranian Journal of Basic Medical Sciences
Subjects:	Anti-inflammatory agents Gambogic acid MAPK NF-κB p38 RAW 264.7 cells
Online Access:	http://ijbms.mums.ac.ir/article_10758_6ec1b1cfe4edbd6abf8f8f687093e92e.pdf

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