NLRP3 inflammasome-mediated cytokine production and pyroptosis cell death in breast cancer

NLRP3 inflammasome-mediated cytokine production and pyroptosis cell death in breast cancer

Abstract Breast cancer is the most diagnosed malignancy in women. Increasing evidence has highlighted the importance of chronic inflammation at the local and/or systemic level in breast cancer pathobiology, influencing its progression, metastatic potential and therapeutic outcome by altering the tum...

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Bibliographic Details
Main Authors: Sara Socorro Faria, Susan Costantini, Vladmir Cláudio Cordeiro de Lima, Victor Pianna de Andrade, Mickaël Rialland, Rebe Cedric, Alfredo Budillon, Kelly Grace Magalhães
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Journal of Biomedical Science
Subjects:
Breast cancer
Gasdermins
IL-1β
NLRP3 inflammasome
Online Access:https://doi.org/10.1186/s12929-021-00724-8

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