Association of imputed prostate cancer transcriptome with disease risk reveals novel mechanisms
In prostate cancer, investigating aberrant gene expression may shed light on disease etiology. Here, the authors imputed expression transcriptome-wide for 233,955 European ancestry men, discovering and replicating the associations between prostatic expression for select genes and prostate cancer ris...
Main Authors: | Nima C. Emami, Linda Kachuri, Travis J. Meyers, Rajdeep Das, Joshua D. Hoffman, Thomas J. Hoffmann, Donglei Hu, Jun Shan, Felix Y. Feng, Elad Ziv, Stephen K. Van Den Eeden, John S. Witte |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2019-07-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-019-10808-7 |
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