Precurarization with Rocuronium Prevents Succinylcholine induced Hyperkalemia
Background: To assess the effects of Rocuronium pretreatment on Succinylcholine induced rise in serum potassium. Methods: In this randomized controlled experimental study, sixty adults ASA I or II patients who presented for elective general surgical procedures were included. The patients were divid...
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| Format: | Article |
| Language: | English |
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Rawalpindi Medical University
2012-12-01
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| Series: | Journal of Rawalpindi Medical College |
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| Online Access: | https://www.journalrmc.com/index.php/JRMC/article/view/571 |
| Summary: | Background: To assess the effects of Rocuronium
pretreatment on Succinylcholine induced rise in serum
potassium.
Methods: In this randomized controlled experimental
study, sixty adults ASA I or II patients who presented for
elective general surgical procedures were included. The
patients were divided in two groups of thirty each by a
simple randomization. Group "A" received succinylcholine
and group "B" received precurarization dose of rocuronium
followed by succinylcholine for intubation. Venous blood
samples were obtained for estimation of serum potassium
(K+) at 0 minutes and after five minutes of intubation.
Results: There was a significant rise in serum K+ level
from the start of the study to five minutes in group A (p <
0.001). In group B, increase in serum K+ level from start of
the study to five minutes was significant (p = 0.001) but it
remained within the normal range. The increase in serum
K+ level was significantly more in group A as compared to
group B (p < 0.001).
Conclusion: Pretreatment with rocuronium prevents
the rise in serum potassium induced by succinylcholine
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| ISSN: | 1683-3562 1683-3570 |