RP-HPLC method development and validation for bedaquiline fumarate to evaluate its forced degradation behaviour and stability in official dissolution media
Abstract Background A simple, rapid and accurate reverse phase RP-HPLC method for the validation of antitubercular drug bedaquiline fumarate (BQF) was developed. The stability and forced degradation behaviour of bedaquiline fumarate (BQF) in official dissolution media (0.01 N HCl) and methanol were...
Main Authors: | Vishwas Pardhi, Geetanjali Pant, S. J. S. Flora |
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Format: | Article |
Language: | English |
Published: |
SpringerOpen
2020-07-01
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Series: | Future Journal of Pharmaceutical Sciences |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s43094-020-00061-x |
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