Systematic Analysis of the Associations between Adverse Drug Reactions and Pathways
Adverse drug reactions (ADRs) are responsible for drug candidate failure during clinical trials. It is crucial to investigate biological pathways contributing to ADRs. Here, we applied a large-scale analysis to identify overrepresented ADR-pathway combinations through merging clinical phenotypic dat...
Main Authors: | Xiaowen Chen, Yanqiu Wang, Pingping Wang, Baofeng Lian, Chunquan Li, Jing Wang, Xia Li, Wei Jiang |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2015-01-01
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Series: | BioMed Research International |
Online Access: | http://dx.doi.org/10.1155/2015/670949 |
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