Respiratory syncytial virus infection as a cause of hospitalization in population under 1 year in Colombia
Objective: to determine the frequency, complications and seasonality at which respira- tory syncytial virus (RSV) infection of the lower respiratory tract causes hospitalization in infants of age 1 year or less in 6 cities of Colombia. Methods: one-year prospective multicentric observational study t...
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doaj-eaabcaedfe604390b797a3aaaa595c6b2020-11-24T23:02:41ZporElsevierJornal de Pediatria (Versão em Português)2255-55362013-11-0189654454810.1016/j.jpedp.2013.04.003Respiratory syncytial virus infection as a cause of hospitalization in population under 1 year in ColombiaJuan Gabriel Piñeros0Hernando Baquero1Jaime Bastidas2Jorge García3Oscar Ovalle4Carlos M. Patiño5Juan C. Restrepo6Hospital Universitario Fundación Santa Fé de Bogotá, Bogotá, ColômbiaFundación Universidad del Norte, Barranquilla, ColômbiaClínica Farallones, Universidad del Valle, Cali, ColômbiaClínica Materno-Infantil San Luis, Bucaramanga, ColômbiaClínica Materno-Infantil de Saludcoop, Bogotá, ColômbiaClínica de las Américas, Medellín, ColômbiaHospital San Jorge de Pereira, Pereira, ColômbiaObjective: to determine the frequency, complications and seasonality at which respira- tory syncytial virus (RSV) infection of the lower respiratory tract causes hospitalization in infants of age 1 year or less in 6 cities of Colombia. Methods: one-year prospective multicentric observational study that included 717 patients presenting to the emergency department with respiratory symptoms in 6 cities of Colombia. Hospitalized children were tested for RSV with an immunofluorescence rapid test in nasopharyngeal secretions. Descriptive and statistical analyses of the popu- lation were conducted. Results: the study population included 717 patients with a mean age of 3.6 months (SD 3.25), 4:3 male: female ratio and a positive RSV LRTI prevalence of 30.0% (216 infants/City, range 26.0 - 49.0%). Risk factors for RSV LRTI were found in 8.2% of the population, of which 28.8% were RSV positive. RSV positive and negative groups were compared using a two-tailed t test with 95.0%CI, p < 0.05. No statistically significant differences were found. All cities presented specific year trimesters in the occurrence of RSV LRTI. Conclusions: the RSV caused 1 in 3 LRTI hospitalizations in the population, with an inci- dence of 30.0%. This confirms a continuous circulation of RSV in Colombia varying by geographic location.http://www.sciencedirect.com/science/article/pii/S2255553613001183Respiratory syncytial virusLower respiratory tract infectionHospitalization |
collection |
DOAJ |
language |
Portuguese |
format |
Article |
sources |
DOAJ |
author |
Juan Gabriel Piñeros Hernando Baquero Jaime Bastidas Jorge García Oscar Ovalle Carlos M. Patiño Juan C. Restrepo |
spellingShingle |
Juan Gabriel Piñeros Hernando Baquero Jaime Bastidas Jorge García Oscar Ovalle Carlos M. Patiño Juan C. Restrepo Respiratory syncytial virus infection as a cause of hospitalization in population under 1 year in Colombia Jornal de Pediatria (Versão em Português) Respiratory syncytial virus Lower respiratory tract infection Hospitalization |
author_facet |
Juan Gabriel Piñeros Hernando Baquero Jaime Bastidas Jorge García Oscar Ovalle Carlos M. Patiño Juan C. Restrepo |
author_sort |
Juan Gabriel Piñeros |
title |
Respiratory syncytial virus infection as a cause of hospitalization in population under 1 year in Colombia |
title_short |
Respiratory syncytial virus infection as a cause of hospitalization in population under 1 year in Colombia |
title_full |
Respiratory syncytial virus infection as a cause of hospitalization in population under 1 year in Colombia |
title_fullStr |
Respiratory syncytial virus infection as a cause of hospitalization in population under 1 year in Colombia |
title_full_unstemmed |
Respiratory syncytial virus infection as a cause of hospitalization in population under 1 year in Colombia |
title_sort |
respiratory syncytial virus infection as a cause of hospitalization in population under 1 year in colombia |
publisher |
Elsevier |
series |
Jornal de Pediatria (Versão em Português) |
issn |
2255-5536 |
publishDate |
2013-11-01 |
description |
Objective: to determine the frequency, complications and seasonality at which respira- tory syncytial virus (RSV) infection of the lower respiratory tract causes hospitalization in infants of age 1 year or less in 6 cities of Colombia.
Methods: one-year prospective multicentric observational study that included 717 patients presenting to the emergency department with respiratory symptoms in 6 cities of Colombia. Hospitalized children were tested for RSV with an immunofluorescence rapid test in nasopharyngeal secretions. Descriptive and statistical analyses of the popu- lation were conducted.
Results: the study population included 717 patients with a mean age of 3.6 months (SD 3.25), 4:3 male: female ratio and a positive RSV LRTI prevalence of 30.0% (216 infants/City, range 26.0 - 49.0%). Risk factors for RSV LRTI were found in 8.2% of the population, of which 28.8% were RSV positive. RSV positive and negative groups were compared using a two-tailed t test with 95.0%CI, p < 0.05. No statistically significant differences were found. All cities presented specific year trimesters in the occurrence of RSV LRTI.
Conclusions: the RSV caused 1 in 3 LRTI hospitalizations in the population, with an inci- dence of 30.0%. This confirms a continuous circulation of RSV in Colombia varying by geographic location. |
topic |
Respiratory syncytial virus Lower respiratory tract infection Hospitalization |
url |
http://www.sciencedirect.com/science/article/pii/S2255553613001183 |
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