An atypical presentation and diagnostic dilemma of sickle cell disease
A 5½ year old male child of a consanguineous couple presented with moderately high fever, hepatosplenomegaly and severe pain in the left upper quadrant of the abdomen for four days. On examination, the child was found severely anemic, ill-looking and mildly icteric but the abdomen was soft and non-t...
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doaj-eac399bbd0ab4f28a5c7d58397488d272020-11-24T22:08:17ZengBangabandhu Sheikh Mujib Medical UniversityBangabandhu Sheikh Mujib Medical University Journal2074-29082224-77502017-06-0110210.3329/bsmmuj.v10i2.3270521087An atypical presentation and diagnostic dilemma of sickle cell diseaseMohammad Mizanur Rahman0Md. Monirul Islam1Lutfunnahar Khan2Department of Hematology, Armed Forces Institute of Pathology, Dhaka Cantonment, DhakaDepartment of Hematology, Armed Forces Institute of Pathology, Dhaka Cantonment, DhakaDepartment of Hematology, Armed Forces Institute of Pathology, Dhaka Cantonment, DhakaA 5½ year old male child of a consanguineous couple presented with moderately high fever, hepatosplenomegaly and severe pain in the left upper quadrant of the abdomen for four days. On examination, the child was found severely anemic, ill-looking and mildly icteric but the abdomen was soft and non-tender. Radiological investigations and ultrasonography of the whole abdomen revealed the diagnosis of space occupying lesions which may be either due to splenic abscess/cyst or leukemia/lymphoma. However, blood film revealed the features of hereditary hemolytic anemia and later on hemoglobin electrophoresis initially commented as HbSbeta thalassemia but subsequent family screening of the patient turned out to a case of homozygous sickle cell anemia or sickle cell disease. To resolve such diagnostic dilemma, it is very much essential to analyze critically the history including family history, clinical and physical findings as well as investigational findings. https://www.banglajol.info/index.php/BSMMUJ/article/view/32705AtypicalCase reportDiagnostic dilemmaSickle cell disease |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Mohammad Mizanur Rahman Md. Monirul Islam Lutfunnahar Khan |
spellingShingle |
Mohammad Mizanur Rahman Md. Monirul Islam Lutfunnahar Khan An atypical presentation and diagnostic dilemma of sickle cell disease Bangabandhu Sheikh Mujib Medical University Journal Atypical Case report Diagnostic dilemma Sickle cell disease |
author_facet |
Mohammad Mizanur Rahman Md. Monirul Islam Lutfunnahar Khan |
author_sort |
Mohammad Mizanur Rahman |
title |
An atypical presentation and diagnostic dilemma of sickle cell disease |
title_short |
An atypical presentation and diagnostic dilemma of sickle cell disease |
title_full |
An atypical presentation and diagnostic dilemma of sickle cell disease |
title_fullStr |
An atypical presentation and diagnostic dilemma of sickle cell disease |
title_full_unstemmed |
An atypical presentation and diagnostic dilemma of sickle cell disease |
title_sort |
atypical presentation and diagnostic dilemma of sickle cell disease |
publisher |
Bangabandhu Sheikh Mujib Medical University |
series |
Bangabandhu Sheikh Mujib Medical University Journal |
issn |
2074-2908 2224-7750 |
publishDate |
2017-06-01 |
description |
A 5½ year old male child of a consanguineous couple presented with moderately high fever, hepatosplenomegaly and severe pain in the left upper quadrant of the abdomen for four days. On examination, the child was found severely anemic, ill-looking and mildly icteric but the abdomen was soft and non-tender. Radiological investigations and ultrasonography of the whole abdomen revealed the diagnosis of space occupying lesions which may be either due to splenic abscess/cyst or leukemia/lymphoma. However, blood film revealed the features of hereditary hemolytic anemia and later on hemoglobin electrophoresis initially commented as HbSbeta thalassemia but subsequent family screening of the patient turned out to a case of homozygous sickle cell anemia or sickle cell disease. To resolve such diagnostic dilemma, it is very much essential to analyze critically the history including family history, clinical and physical findings as well as investigational findings.
|
topic |
Atypical Case report Diagnostic dilemma Sickle cell disease |
url |
https://www.banglajol.info/index.php/BSMMUJ/article/view/32705 |
work_keys_str_mv |
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