TP53 Status and Response to Treatment in Breast Cancers
The p53 wild-type protein plays an important role in cells as is shown by its fine regulation at different levels. Since its discovery, numerous mutations have been described. In breast cancers, p53 is mutated in almost 30% of cases, with a higher frequency in some tumor subtypes. TP53 mutation is r...
Main Authors: | Mariana Varna, Guilhem Bousquet, Louis-François Plassa, Philippe Bertheau, Anne Janin |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2011-01-01
|
Series: | Journal of Biomedicine and Biotechnology |
Online Access: | http://dx.doi.org/10.1155/2011/284584 |
Similar Items
-
Exquisite sensitivity of TP53 mutant and basal breast cancers to a dose-dense epirubicin-cyclophosphamide regimen.
by: Philippe Bertheau, et al.
Published: (2007-03-01) -
Breast cancer survival predicted by TP53 mutation status differs markedly depending on treatment
by: Nathan A. Ungerleider, et al.
Published: (2018-10-01) -
Impact of TP53 mutations in breast cancer: Clinicopathological features and prognosisImpact of TP53 mutations in breast CA
by: Xuerui Li, et al.
Published: (2020-07-01) -
Value of TP53 status for predicting response to neoadjuvant chemotherapy in breast cancer: a meta-analysis.
by: Min-Bin Chen, et al.
Published: (2012-01-01) -
Germline and somatic studies in the TP53 gene in breast and other cancers
by: Eeles, Rosalind Anne
Published: (2000)