Human African trypanosomiasis caused by Trypanosoma brucei gambiense: The first case report in China

Human African trypanosomiasis caused by Trypanosoma brucei gambiense: The first case report in China

We report the first imported case in China of human African trypanosomiasis (HAT), caused by Trypanosoma brucei gambiense, in a sailor returning from Gabon in 2014. The diagnosis was delayed and relapse led to death, despite treatment with eflornithine, as recommended by the World Health Organizatio...

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Main Authors: Nian Chen, Ke Jin, Jingjing Xu, Jianfu Zhang, Yali Weng
Format: Article
Language:English
Published: Elsevier 2019-02-01
Series:International Journal of Infectious Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S120197121834582X
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spelling doaj-ead51aa8b6f84a6cb2ec8fe54dcdfc1e2020-11-24T21:39:53ZengElsevierInternational Journal of Infectious Diseases1201-97122019-02-01793436Human African trypanosomiasis caused by Trypanosoma brucei gambiense: The first case report in ChinaNian Chen0Ke Jin1Jingjing Xu2Jianfu Zhang3Yali Weng4Department of Infectious Diseases, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, 210029, ChinaDepartment of Infectious Diseases, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, 210029, ChinaDepartment of Respiration, Wuxi Xishan People’s Hospital, Wuxi, 214011, ChinaDepartment of Hematology Laboratory, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, 210029, ChinaDepartment of Infectious Diseases, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, 210029, China; Corresponding author.We report the first imported case in China of human African trypanosomiasis (HAT), caused by Trypanosoma brucei gambiense, in a sailor returning from Gabon in 2014. The diagnosis was delayed and relapse led to death, despite treatment with eflornithine, as recommended by the World Health Organization for late-stage HAT. This case shows that early diagnosis of HAT and close follow-up with proper retreatment are critical. Keywords: Human African Trypanosomiasis, Diagnosis, Treatment, Relapsehttp://www.sciencedirect.com/science/article/pii/S120197121834582X
collection DOAJ
language English
format Article
sources DOAJ
author Nian Chen
Ke Jin
Jingjing Xu
Jianfu Zhang
Yali Weng
spellingShingle Nian Chen
Ke Jin
Jingjing Xu
Jianfu Zhang
Yali Weng
Human African trypanosomiasis caused by Trypanosoma brucei gambiense: The first case report in China
International Journal of Infectious Diseases
author_facet Nian Chen
Ke Jin
Jingjing Xu
Jianfu Zhang
Yali Weng
author_sort Nian Chen
title Human African trypanosomiasis caused by Trypanosoma brucei gambiense: The first case report in China
title_short Human African trypanosomiasis caused by Trypanosoma brucei gambiense: The first case report in China
title_full Human African trypanosomiasis caused by Trypanosoma brucei gambiense: The first case report in China
title_fullStr Human African trypanosomiasis caused by Trypanosoma brucei gambiense: The first case report in China
title_full_unstemmed Human African trypanosomiasis caused by Trypanosoma brucei gambiense: The first case report in China
title_sort human african trypanosomiasis caused by trypanosoma brucei gambiense: the first case report in china
publisher Elsevier
series International Journal of Infectious Diseases
issn 1201-9712
publishDate 2019-02-01
description We report the first imported case in China of human African trypanosomiasis (HAT), caused by Trypanosoma brucei gambiense, in a sailor returning from Gabon in 2014. The diagnosis was delayed and relapse led to death, despite treatment with eflornithine, as recommended by the World Health Organization for late-stage HAT. This case shows that early diagnosis of HAT and close follow-up with proper retreatment are critical. Keywords: Human African Trypanosomiasis, Diagnosis, Treatment, Relapse
url http://www.sciencedirect.com/science/article/pii/S120197121834582X
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AT kejin humanafricantrypanosomiasiscausedbytrypanosomabruceigambiensethefirstcasereportinchina
AT jingjingxu humanafricantrypanosomiasiscausedbytrypanosomabruceigambiensethefirstcasereportinchina
AT jianfuzhang humanafricantrypanosomiasiscausedbytrypanosomabruceigambiensethefirstcasereportinchina
AT yaliweng humanafricantrypanosomiasiscausedbytrypanosomabruceigambiensethefirstcasereportinchina
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