Intermedin protects against sepsis by concurrently re-establishing the endothelial barrier and alleviating inflammatory responses
Sepsis is a life-threatening condition. Here, the authors show that intermedin alleviates organ injury and decreases mortality in septic mice by concurrently alleviating vascular leakage and inflammatory responses. Patients with high intermedin levels exhibit a low risk of shock, lower severity scor...
Main Authors: | Fei Xiao, Denian Wang, Lingmiao Kong, Min Li, Zhongxue Feng, Bingxing Shuai, Lijun Wang, Yong’gang Wei, Hongyu Li, Sisi Wu, Chun Tan, Huan Zhao, Xuejiao Hu, Jin Liu, Yan Kang, Xuelian Liao, Yan Zhou, Wei Zhang |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2018-07-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-018-05062-2 |
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