Improved methodical approach for quantitative BRET analysis of G Protein Coupled Receptor dimerization.

G Protein Coupled Receptors (GPCR) can form dimers or higher ordered oligomers, the process of which can remarkably influence the physiological and pharmacological function of these receptors. Quantitative Bioluminescence Resonance Energy Transfer (qBRET) measurements are the gold standards to prove...

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Bibliographic Details
Main Authors: Bence Szalai, Péter Hoffmann, Susanne Prokop, László Erdélyi, Péter Várnai, László Hunyady
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4201472?pdf=render