Viral Proteins Mediate Upregulation of Negative Regulatory Factors Causing Down-Modulated Dendritic Cell Functions In Chronic Hepatitis C Virus Infection

Viral Proteins Mediate Upregulation of Negative Regulatory Factors Causing Down-Modulated Dendritic Cell Functions In Chronic Hepatitis C Virus Infection

Stunted cellular immune response against a narrow range of epitopes is the hallmark of chronic hepatitis C infection, but the underneath molecular mechanisms have not been well elucidated. Suboptimal antigen presentation through defective antigen presenting cells, have been suggested. The myeloid de...

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Bibliographic Details
Main Authors: Deepa Rana, Yogesh K Chawla, Anjay Duseja, Radha K Dhiman, Sunil K Arora
Format: Article
Language:English
Published: European Medical Journal 2013-12-01
Series:European Medical Journal Hepatology
Subjects:
Dendritic Cells
HCV-NS5 Protein
Hepatitis C Virus
IDO
PDL1
SOCS3
Online Access:http://emjreviews.com/wp-content/uploads/9.-DeepaRana-et-al..pdf

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http://emjreviews.com/wp-content/uploads/9.-DeepaRana-et-al..pdf

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