Identification of HIV transmitting CD11c+ human epidermal dendritic cells
Composition and function of immune populations at barrier surfaces is crucial for response to infection. Here, the authors identify a population of dendritic cells in human epidermis, abundant in anogenital epithelia and distinct from Langerhans cells by surface phenotype and by high capacity for HI...
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2019-06-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-019-10697-w |
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doaj-eb12f23a92dd489b8e91e926a319cbf12021-05-11T11:30:27ZengNature Publishing GroupNature Communications2041-17232019-06-0110111510.1038/s41467-019-10697-wIdentification of HIV transmitting CD11c+ human epidermal dendritic cellsKirstie M. Bertram0Rachel A. Botting1Heeva Baharlou2Jake W. Rhodes3Hafsa Rana4J. Dinny Graham5Ellis Patrick6James Fletcher7Toby M. Plasto8Naomi R. Truong9Caroline Royle10Chloe M. Doyle11Orion Tong12Najla Nasr13Laith Barnouti14Mark P. Kohout15Andrew J. Brooks16Michael P. Wines17Peter Haertsch18Jake Lim19Martijn P. Gosselink20Grahame Ctercteko21Jacob D. Estes22Melissa J. Churchill23Paul U. Cameron24Eric Hunter25Muzlifah A. Haniffa26Anthony L. Cunningham27Andrew N. Harman28Centre for Virus Research, The Westmead Institute for Medical ResearchCentre for Virus Research, The Westmead Institute for Medical ResearchCentre for Virus Research, The Westmead Institute for Medical ResearchCentre for Virus Research, The Westmead Institute for Medical ResearchCentre for Virus Research, The Westmead Institute for Medical ResearchCentre for Virus Research, The Westmead Institute for Medical ResearchCentre for Virus Research, The Westmead Institute for Medical ResearchInstitute of Cellular Medicine, Newcastle UniversityCentre for Virus Research, The Westmead Institute for Medical ResearchCentre for Virus Research, The Westmead Institute for Medical ResearchCentre for Virus Research, The Westmead Institute for Medical ResearchCentre for Virus Research, The Westmead Institute for Medical ResearchCentre for Virus Research, The Westmead Institute for Medical ResearchCentre for Virus Research, The Westmead Institute for Medical ResearchAustralia Plastic SurgeryAustralia Plastic SurgeryWestmead HospitalRoyal North Shore HospitalBurns Unit, Concord Repatriation General HospitalDr Jake Lim PLCCentre for Virus Research, The Westmead Institute for Medical ResearchCentre for Virus Research, The Westmead Institute for Medical ResearchAIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research IncSchool of Health and Biomedical Sciences, College of Science, Engineering and Health, RMIT UniversityThe Peter Doherty Institute for Infection and ImmunityEmory Vaccine CenterInstitute of Cellular Medicine, Newcastle UniversityCentre for Virus Research, The Westmead Institute for Medical ResearchCentre for Virus Research, The Westmead Institute for Medical ResearchComposition and function of immune populations at barrier surfaces is crucial for response to infection. Here, the authors identify a population of dendritic cells in human epidermis, abundant in anogenital epithelia and distinct from Langerhans cells by surface phenotype and by high capacity for HIV infection and transmission.https://doi.org/10.1038/s41467-019-10697-w |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Kirstie M. Bertram Rachel A. Botting Heeva Baharlou Jake W. Rhodes Hafsa Rana J. Dinny Graham Ellis Patrick James Fletcher Toby M. Plasto Naomi R. Truong Caroline Royle Chloe M. Doyle Orion Tong Najla Nasr Laith Barnouti Mark P. Kohout Andrew J. Brooks Michael P. Wines Peter Haertsch Jake Lim Martijn P. Gosselink Grahame Ctercteko Jacob D. Estes Melissa J. Churchill Paul U. Cameron Eric Hunter Muzlifah A. Haniffa Anthony L. Cunningham Andrew N. Harman |
spellingShingle |
Kirstie M. Bertram Rachel A. Botting Heeva Baharlou Jake W. Rhodes Hafsa Rana J. Dinny Graham Ellis Patrick James Fletcher Toby M. Plasto Naomi R. Truong Caroline Royle Chloe M. Doyle Orion Tong Najla Nasr Laith Barnouti Mark P. Kohout Andrew J. Brooks Michael P. Wines Peter Haertsch Jake Lim Martijn P. Gosselink Grahame Ctercteko Jacob D. Estes Melissa J. Churchill Paul U. Cameron Eric Hunter Muzlifah A. Haniffa Anthony L. Cunningham Andrew N. Harman Identification of HIV transmitting CD11c+ human epidermal dendritic cells Nature Communications |
author_facet |
Kirstie M. Bertram Rachel A. Botting Heeva Baharlou Jake W. Rhodes Hafsa Rana J. Dinny Graham Ellis Patrick James Fletcher Toby M. Plasto Naomi R. Truong Caroline Royle Chloe M. Doyle Orion Tong Najla Nasr Laith Barnouti Mark P. Kohout Andrew J. Brooks Michael P. Wines Peter Haertsch Jake Lim Martijn P. Gosselink Grahame Ctercteko Jacob D. Estes Melissa J. Churchill Paul U. Cameron Eric Hunter Muzlifah A. Haniffa Anthony L. Cunningham Andrew N. Harman |
author_sort |
Kirstie M. Bertram |
title |
Identification of HIV transmitting CD11c+ human epidermal dendritic cells |
title_short |
Identification of HIV transmitting CD11c+ human epidermal dendritic cells |
title_full |
Identification of HIV transmitting CD11c+ human epidermal dendritic cells |
title_fullStr |
Identification of HIV transmitting CD11c+ human epidermal dendritic cells |
title_full_unstemmed |
Identification of HIV transmitting CD11c+ human epidermal dendritic cells |
title_sort |
identification of hiv transmitting cd11c+ human epidermal dendritic cells |
publisher |
Nature Publishing Group |
series |
Nature Communications |
issn |
2041-1723 |
publishDate |
2019-06-01 |
description |
Composition and function of immune populations at barrier surfaces is crucial for response to infection. Here, the authors identify a population of dendritic cells in human epidermis, abundant in anogenital epithelia and distinct from Langerhans cells by surface phenotype and by high capacity for HIV infection and transmission. |
url |
https://doi.org/10.1038/s41467-019-10697-w |
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