Modulation of MAPK and NF-κB Signaling Pathways by Antioxidant Therapy in Skeletal Muscle of Heart Failure Rats
Background/Aims: Although increased oxidative stress plays a role in heart failure (HF)-induced skeletal myopathy, signaling pathways involved in muscle changes and the role of antioxidant agents have been poorly addressed. We evaluated the effects of N-acetylcysteine (NAC) on intracellular signalin...
Main Authors: | Paula F. Martinez, Camila Bonomo, Daniele M. Guizoni, Silvio A. Oliveira Junior, Ricardo L. Damatto, Marcelo D.M. Cezar, Aline R.R. Lima, Luana U. Pagan, Fabio R. Seiva, Renata T. Bueno, Denise C. Fernandes, Francisco R. Laurindo, Leonardo A.M. Zornoff, Katashi Okoshi, Marina P. Okoshi |
---|---|
Format: | Article |
Language: | English |
Published: |
Cell Physiol Biochem Press GmbH & Co KG
2016-06-01
|
Series: | Cellular Physiology and Biochemistry |
Subjects: | |
Online Access: | http://www.karger.com/Article/FullText/445631 |
Similar Items
-
Influence of N-Acetylcysteine on Oxidative Stress in Slow-Twitch Soleus Muscle of Heart Failure Rats
by: Paula F. Martinez, et al.
Published: (2015-01-01) -
Heart Failure-Induced Diaphragm Myopathy
by: Aline Regina Ruiz Lima, et al.
Published: (2014-07-01) -
Cellular and Molecular Mechanisms Underlying Congenital Myopathy-related Weakness
by: Lindqvist, Johan
Published: (2014) -
Cored in the act: the use of models to understand core myopathies
by: Aurora Fusto, et al.
Published: (2019-12-01) -
Exploration de l'hétérogénéité mutationnelle et de ses conséquences pathologiques dans les myopathies : analyses des mécanismes et développement d'outils thérapeutiques
by: Dionnet, Eugénie
Published: (2016)