Epigenetic Delay in the Neurodevelopmental Trajectory of DNA Methylation States in Autism Spectrum Disorders

Epigenetic Delay in the Neurodevelopmental Trajectory of DNA Methylation States in Autism Spectrum Disorders

Autism spectrum disorders (ASD) are hypothesized to originate in utero from perturbations in neural stem cell niche regions of the developing brain. Dynamic epigenetic processes including DNA methylation are integral to coordinating typical brain development. However, the extent and consequences of...

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Bibliographic Details
Main Authors: Michael J. Corley, Nauru Vargas-Maya, Alina P. S. Pang, Annette Lum-Jones, Dongmei Li, Vedbar Khadka, Razvan Sultana, D. Caroline Blanchard, Alika K. Maunakea
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Genetics
Subjects:
autism
DNA methylation
neurodevelopment
epigenetics
ASD
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00907/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2019.00907/full

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