Physical Activity and Nutrition: Two Promising Strategies for Telomere Maintenance?

• Main Authors: Estelle Balan, Anabelle Decottignies, Louise Deldicque
• Format: Article
• Language: English
• Published: MDPI AG 2018-12-01
• Series: Nutrients
• Subjects: aging; exercise; diet; telomerase; TERRA; telomere length; senescence
• Online Access: https://www.mdpi.com/2072-6643/10/12/1942

As the world demographic structure is getting older, highlighting strategies to counteract age-related diseases is a major public health concern. Telomeres are nucleoprotein structures that serve as guardians of genome stability by ensuring protection against both cell death and senescence. A hallmark of biological aging, telomere health is determined throughout the lifespan by a combination of both genetic and non-genetic influences. This review summarizes data from recently published studies looking at the effect of lifestyle variables such as nutrition and physical activity on telomere dynamics.