Magnetic Nanoparticle Mediated Steroid Delivery Mitigates Cisplatin Induced Hearing Loss

Magnetic Nanoparticle Mediated Steroid Delivery Mitigates Cisplatin Induced Hearing Loss

Cisplatin (cis-diamminedichloroplatinum) is widely used as a chemotherapeutic drug for genitourinary, breast, lung and head and neck cancers. Though effective in inducing apoptosis in cancer cells, cisplatin treatment causes severe hearing loss among patients. Steroids have been shown to mitigate ci...

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Bibliographic Details
Main Authors: Bharath Ramaswamy, Soumen Roy, Andrea B. Apolo, Benjamin Shapiro, Didier A. Depireux
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Cellular Neuroscience
Subjects:
cisplatin
ototoxicity
magnetic nanoparticles
drug delivery
hair cells
Online Access:http://journal.frontiersin.org/article/10.3389/fncel.2017.00268/full

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