Impact of monthly headache days on anxiety, depression and disability in migraine patients: results from the Spanish Atlas
Abstract Identifying highly disabled patients or at high risk of psychiatric comorbidity is crucial for migraine management. The burden of migraine increases with headache frequency, but the number of headache days (HDs) per month after which disability becomes severe or the risk of anxiety and depr...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-04-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-87352-2 |
id |
doaj-eb288762b19f4e68a41e57b309aae23f |
---|---|
record_format |
Article |
spelling |
doaj-eb288762b19f4e68a41e57b309aae23f2021-04-18T11:36:16ZengNature Publishing GroupScientific Reports2045-23222021-04-011111910.1038/s41598-021-87352-2Impact of monthly headache days on anxiety, depression and disability in migraine patients: results from the Spanish AtlasP. Irimia0M. Garrido-Cumbrera1S. Santos-Lasaosa2M. Aguirre-Vazquez3J. Correa-Fernández4I. Colomina5P. Pozo-Rosich6Department of Neurology, Clínica Universidad de NavarraHealth and Territory Research (HTR), Universidad de SevillaHeadache Study Group of the Spanish Neurological Society (GECSEN)Novartis Farmacéutica SpainHealth and Territory Research (HTR), Universidad de SevillaSpanish Patient’s Association of Migraine and Headache (AEMICE)Headache Study Group of the Spanish Neurological Society (GECSEN)Abstract Identifying highly disabled patients or at high risk of psychiatric comorbidity is crucial for migraine management. The burden of migraine increases with headache frequency, but the number of headache days (HDs) per month after which disability becomes severe or the risk of anxiety and depression is higher has not been established. Here, we estimate the number of HDs per month after which migraine is associated with higher risk of anxiety and depression, severe disability and lower quality of life. We analysed 468 migraine patients (mean age 36.8 ± 10.7; 90.2% female), of whom 38.5% had ≥ 15 HDs per month. Our results show a positive linear correlation between the number of HDs per month and the risk of anxiety (r = 0.273; p < 0.001), depression (r = 0.337; p < 0.001) and severe disability (r = 0.519; p < 0.001). The risk of anxiety is higher in patients having ≥ 3HDs per month, and those with ≥ 19HDs per month are at risk of depression. Moreover, patients suffering ≥ 10HDs per month have very severe disability. Our results suggest that migraine patients with ≥ 10HDs per month are very disabled and also that those with ≥ 3HDs per month should be screened for anxiety.https://doi.org/10.1038/s41598-021-87352-2 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
P. Irimia M. Garrido-Cumbrera S. Santos-Lasaosa M. Aguirre-Vazquez J. Correa-Fernández I. Colomina P. Pozo-Rosich |
spellingShingle |
P. Irimia M. Garrido-Cumbrera S. Santos-Lasaosa M. Aguirre-Vazquez J. Correa-Fernández I. Colomina P. Pozo-Rosich Impact of monthly headache days on anxiety, depression and disability in migraine patients: results from the Spanish Atlas Scientific Reports |
author_facet |
P. Irimia M. Garrido-Cumbrera S. Santos-Lasaosa M. Aguirre-Vazquez J. Correa-Fernández I. Colomina P. Pozo-Rosich |
author_sort |
P. Irimia |
title |
Impact of monthly headache days on anxiety, depression and disability in migraine patients: results from the Spanish Atlas |
title_short |
Impact of monthly headache days on anxiety, depression and disability in migraine patients: results from the Spanish Atlas |
title_full |
Impact of monthly headache days on anxiety, depression and disability in migraine patients: results from the Spanish Atlas |
title_fullStr |
Impact of monthly headache days on anxiety, depression and disability in migraine patients: results from the Spanish Atlas |
title_full_unstemmed |
Impact of monthly headache days on anxiety, depression and disability in migraine patients: results from the Spanish Atlas |
title_sort |
impact of monthly headache days on anxiety, depression and disability in migraine patients: results from the spanish atlas |
publisher |
Nature Publishing Group |
series |
Scientific Reports |
issn |
2045-2322 |
publishDate |
2021-04-01 |
description |
Abstract Identifying highly disabled patients or at high risk of psychiatric comorbidity is crucial for migraine management. The burden of migraine increases with headache frequency, but the number of headache days (HDs) per month after which disability becomes severe or the risk of anxiety and depression is higher has not been established. Here, we estimate the number of HDs per month after which migraine is associated with higher risk of anxiety and depression, severe disability and lower quality of life. We analysed 468 migraine patients (mean age 36.8 ± 10.7; 90.2% female), of whom 38.5% had ≥ 15 HDs per month. Our results show a positive linear correlation between the number of HDs per month and the risk of anxiety (r = 0.273; p < 0.001), depression (r = 0.337; p < 0.001) and severe disability (r = 0.519; p < 0.001). The risk of anxiety is higher in patients having ≥ 3HDs per month, and those with ≥ 19HDs per month are at risk of depression. Moreover, patients suffering ≥ 10HDs per month have very severe disability. Our results suggest that migraine patients with ≥ 10HDs per month are very disabled and also that those with ≥ 3HDs per month should be screened for anxiety. |
url |
https://doi.org/10.1038/s41598-021-87352-2 |
work_keys_str_mv |
AT pirimia impactofmonthlyheadachedaysonanxietydepressionanddisabilityinmigrainepatientsresultsfromthespanishatlas AT mgarridocumbrera impactofmonthlyheadachedaysonanxietydepressionanddisabilityinmigrainepatientsresultsfromthespanishatlas AT ssantoslasaosa impactofmonthlyheadachedaysonanxietydepressionanddisabilityinmigrainepatientsresultsfromthespanishatlas AT maguirrevazquez impactofmonthlyheadachedaysonanxietydepressionanddisabilityinmigrainepatientsresultsfromthespanishatlas AT jcorreafernandez impactofmonthlyheadachedaysonanxietydepressionanddisabilityinmigrainepatientsresultsfromthespanishatlas AT icolomina impactofmonthlyheadachedaysonanxietydepressionanddisabilityinmigrainepatientsresultsfromthespanishatlas AT ppozorosich impactofmonthlyheadachedaysonanxietydepressionanddisabilityinmigrainepatientsresultsfromthespanishatlas |
_version_ |
1721522220196429824 |