Loss of the liver X receptor LXRα/β in peripheral sensory neurons modifies energy expenditure

Loss of the liver X receptor LXRα/β in peripheral sensory neurons modifies energy expenditure

Peripheral neural sensory mechanisms play a crucial role in metabolic regulation but less is known about the mechanisms underlying vagal sensing itself. Recently, we identified an enrichment of liver X receptor alpha and beta (LXRα/β) in the nodose ganglia of the vagus nerve. In this study, we show...

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Bibliographic Details
Main Authors: Virginie Mansuy-Aubert, Laurent Gautron, Syann Lee, Angie L Bookout, Christine M Kusminski, Kai Sun, Yuan Zhang, Philipp E Scherer, David J Mangelsdorf, Joel K Elmquist
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-06-01
Series:eLife
Subjects:
nuclear receptor
sensory neuron
energy expenditure
Online Access:https://elifesciences.org/articles/06667

Internet

https://elifesciences.org/articles/06667

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